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What is CADASIL?

CADASIL is an abbreviation for a long name describing a rare hereditary form of stroke (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy).  The disease usually presents with multiple small strokes, but migraine can also be a prominent feature. CADASIL is a genetic condition caused by a small abnormality (mutation) in a gene called NOTCH3.

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